HPLC with post column derivatisation data collected during the Chemistry of the Antarctic Boundary Layer and the Interface with Snow (CHABLIS) project. CHABLIS was a Natural Environment Research Council (NERC) and Antarctic Funding Initiative (AFI) funded project, aimed at studying the chemistry of the Antarctic Boundary Layer in greater detail, and for a longer duration, than has previously been attempted. Field measurements were carried out at the British Antarctic Survey station, Halley, at the Clean Air Sector Laboratory (CASLab). Year-round measurements began in February 2004, and a summer campaign focussing on oxidants ran during January/February 2005, after which CHABLIS fieldwork ended. The dataset includes mixing ratios (Ozone, CO, HCHO, NO2, and HONO), accumulation and isotope (Na, K, Mg, Ca, F, CH4, Cl, and NO3) concentrations of snow, and meteorological measurements (relative humidity, visibility, dew point, wind speed, and wind direction). Access to this dataset is now public.